We have previously shown that the

2018-10-20

We have previously shown that the piggyBac (PB) transposon modified from moth can efficiently transpose in the mouse and human genomes (Ding et al., 2005). Here we present a gain of function screen in human ES selective serotonin reuptake inhibitor using PB transposon mutagenesis. The transposon is

To gain greater insight into the

2018-10-20

To gain greater insight into the broad applicability for cell delivery, HAMC was investigated for the delivery of adult mouse NSCs (Morshead et al., 1994) to the brain. Significantly more cells were observed when delivered in HAMC versus artificial cerebrospinal fluid (aCSF) controls. Moreover, the

Here we screened eight cardiogenic compounds and found that

2018-10-20

Here, we screened eight cardiogenic compounds and found that a combination of fibroblast growth factor (FGF) 2, FGF10, and vascular endothelial growth factor (VEGF), termed FFV, greatly improved the quality of cardiac reprogramming in mouse fibroblasts under serum-free conditions. FFV treatment acti

Using immunocytochemical analysis we found that LRRK

2018-10-20

Using immunocytochemical analysis, we found that LRRK2 G2019S iPSC-derived sensory neurons displayed neurite aggregations comprised of PD-associated proteins β-tubulin, MAP2, Tau, LRRK2, and SNCA. β-tubulin, a component of Lewy bodies, has been shown to directly interact with LRRK2, which regulates

neuroscience peptides Several strategies have been recently

2018-10-20

Several strategies have been recently developed for CBC cell isolation via cell surface markers and fluorescence-activated cell sorting (FACS; Gracz et al., 2013; King et al., 2012; Merlos-Suarez et al., 2011; Wang et al., 2013). Although they represent considerable advances in the isolation of CBC

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2018-07-29