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To overcome these resistance mechanisms in APL cells
2019-04-19

To overcome these resistance mechanisms in APL cells, a number of drugs have been tested. Tamibarotene is approximately 10 times more potent than ATRA as an in vitro inducer of differentiation, and is chemically more stable than ATRA [5]. Although the precise mechanism of the combination of tamibaro
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A Framework Convention on Global Health FCGH supported by
2019-04-19

A Framework Convention on Global Health (FCGH)—supported by civil society and global leaders—should become the centrepiece of this endeavour (). It would reform global governance for health to enhance accountability, transparency, and civil society participation and protect the right to health in tr
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There are some models of sleep deprivation
2019-04-19

There are some models of sleep deprivation, such as acute or chronic, total or selective sleep deprivation, sleep restriction, or sleep fragmentation. Modifed multiple platform method (MMPM) in our study causes a particularly strong reduction in REM sleep, breaks the sleep continuity. Previous studi
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A total of microorganism species in the old
2019-04-19

A total of 46 microorganism species in the old NICU group and 35 in the new NICU group were isolated, respectively. Klebsiella pneumoniae was the most frequent pathogen in the old NICU group (Table 4), followed by E. coli, Methicillin-resistant Staphylococcus aureus (MRSA), Coagulase-negative Staphy
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br Management of warfarin during pacemaker implantable cardi
2019-04-19

Management of warfarin during pacemaker/implantable cardioverter defibrillator insertion Until recently, warfarin use was halted before PM/ICD insertion and the patient was bridged with intravenous (IV) unfractionated heparin or subcutaneous low-molecular-weight heparin (LMWH) if the thromboembol
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br In mid close to the
2019-04-19

In mid-2015, close to the finish line of the Millennium Development Goals (MDGs), Tanzania has reason to be proud. As Hoviyeh Afnan-Holmes and colleagues note in their Countdown to 2015 case study, Tanzania is on track to achieve MDG4: a two-thirds GSK-923295 in child mortality. The largest gains
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Desde las organizaciones sociales y poblaciones movilizadas
2019-04-19

Desde las organizaciones sociales y poblaciones movilizadas, estas protestas marcan el inicio de un nuevo periodo de distanciamiento frente Nintedanib cost los actores político-institucionales, en particular el Partido Nacionalista que logró aglutinar electoralmente sus críticas y expectativas de ca
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La no intervenci n en los
2019-04-19

La no intervención en los asuntos de otro Estado no significa indiferencia ante los problemas que éste pueda tener. En efecto, algunos usos y gestiones pueden perjudicar order Cyanine3.5 carboxylic acid países vecinos y también al mismo Estado que las realiza. Es por esto que la soberanía no resulta
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Computed tomography images of the chest revealed ground glas
2019-04-18

Computed tomography images of the chest revealed ground-glass opacities and honeycombing, suggestive of pneumonitis. She later required intubation for respiratory failure. To evaluate the troponin elevation, the patient had a transthoracic echocardiogram (Fig. 1A) that demonstrated echodense materia
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Conflicts of interest br Acknowledgments This article
2019-04-18

Conflicts of interest Acknowledgments This article was supported by grants from the Ministry of Science and Technology, Executive Yuan (MOST 103-2314-B-010-043-MY3), and Taipei Veterans General Hospital (V103C-112; V104C-095; and V105C-096). We also appreciate the Clinical Research Core Laborato
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br Introduction Sudden cardiac death
2019-04-18

Introduction Sudden cardiac death (SCD) in patients with low ventricular function remains a substantial problem despite improved medical therapies [1–3]. Many patients require antiarrhythmic drugs to prevent recurrent arrhythmias and reduce the number of shocks from implanted cardioverter-defibri
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br D microCT data Bone volume BV TV
2019-04-18

3D microCT data Bone volume (BV/TV) ranged from 10.8 to 13.5% consistent with the published literature [18]. Trabecular thickness (Tb.Th), trabecular Dihydromyricetin (Tb.Sp), trabecular number (Tb.N) and bone surface per tissue area (BS/TV) values were also consistent with the range published i
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Zebularine Supplier A dual chamber ICD was then implanted an
2019-04-18

A dual-chamber ICD was then implanted and the optimal atrioventricular (AV) interval to obtain the lowest PG was adjusted to a sensed PV interval of 70ms/AV pace of 60ms using echocardiography. After 1 week, the LVOT-PG had decreased to 68mmHg (Fig. 2B); by 3 weeks, it had decreased to 26mmHg (Fig.
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br Introduction The early repolarization ER pattern
2019-04-18

Introduction The early repolarization (ER) pattern has been considered a benign electrocardiographic phenomenon affecting 2–5% of the general population and is most commonly seen in healthy young men and athletes [1–3]. Recent studies have challenged the view of this electrocardiogram (ECG) varia
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Introduction Researchers have long followed the
2019-04-18

Introduction Researchers have long followed the strategy that in order to achieve a fuller understanding of the causes of disease and how they can be prevented, it is necessary to study the biochemical and physiological processes involved in the etiology of disease. As I have argued in previous pap
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