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In humans the effect of
2022-08-26
In humans, the effect of GnRH and hCG on trophoblast invasion was found to be mediated through extracellular matrix remodeling by facilitating the activity of MMP2 and MMP9 [13], [18], [44]. Both Phloretin are collagenases that degrade extracellular matrix. In canines, this has not yet been investi
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Finally we investigated if calpain truncation affects GlyT t
2022-08-26
Finally, we investigated if calpain truncation affects GlyT1 turnover and trafficking. To simulate calpain cleavage at the T602/T603 and G626/S627 sites we constructed GlyT1 transporters missing the last 12 and 36 amino acids. Since the 36 amino SMIP004 receptor truncation also removes all C-termin
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Our results indicate that abcb is likely to
2022-08-26
Our results indicate that abcb5 is likely to be a XT in zebrafish ionocytes, although, like renal cells, the phenotypes observed likely arise from the action of multiple transporters. Zebrafish lack an abcb1 ortholog, and abcb4 and abcb5 have been identified as the P-glycoproteins in zebrafish (Fisc
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br Contributions br Acknowledgements This research was suppo
2022-08-25
Contributions Acknowledgements This research was supported by Natural Sciences and Engineering Research Council (NSERC) Discovery grant No. 341538 and Ontario Graduate Scholarships to HM and VS. Introduction Sexual size dimorphism describes size difference between male and female individua
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In summary metagenome sequencing of paddy soil
2022-08-25
In summary, metagenome sequencing of paddy soil was performed with 55.68 Gb sequences, and subsequent data mining was performed for functional profiles and metabolic pathways. Several GH family proteins, such as amylases, cellulases, xylanases, and galactosidases, were explored in the paddy soil me
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As mentioned earlier two different isoforms of
2022-08-25
As mentioned earlier two different isoforms of TFE3 [16] have been reported viz. the full length (TFE3L) and smaller (TFE3S) without exon 1&2. TFE3S lacks an N-terminal acidic activation domain which is present in TFE3L hence is a dominant negative form of TFE3L [51]. This dominant negative feature
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According to its major function as master regulator of
2022-08-25
According to its major function as master regulator of BA homeostasis, FXR has been shown to have a specific tissue distribution; it is expressed along the entire gastrointestinal tract with a peak in the liver and ileum, as well as in the kidney, and adrenal glands [30], [66], [135]. Low FXR expres
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All data were analyzed using SAS software version SAS
2022-08-25
All data were analyzed using SAS software (version 9.3, SAS Institute Inc., Cary, NC). Because of very low FFAR1 protein detection (at the detection limit or no signal) in 3 H-BHB cows, quantification was not possible within a linear range and therefore these animals were omitted from the statistica
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Recent research has focused on identifying
2022-08-25
Recent research has focused on identifying key agonists and receptors mediating nutrient-induced GLP-1 and insulin secretion. The long-chain fatty 66 4 receptor GPR40 is the most abundant GPCR expressed in islet β cells and is also expressed on intestinal L-cells, where it contributes to GLP-1 relea
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br Discussion In response to an
2022-08-25
Discussion In response to an increase in glucose or DHA concentration, FBPase showed nuclear import and recruitment in a peripheral cell compartment. Interestingly, FBPase and GS were co-recruited to the periphery of the cells. This is precisely the site where glycogen is initially synthesized an
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br Materials and methods Unless stated otherwise all chemica
2022-08-25
Materials and methods Unless stated otherwise, all chemicals were from Sigma-Aldrich and were of the cell culture grade. HL-1 cardiomyocytes were presented by Dr. W.C. Claycomb (Louisiana State University Health Science Center, New Orleans, LA, USA) [8]. Results and discussion Acknowledgeme
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Introduction RNA splicing occurs in the nucleus when noncodi
2022-08-25
Introduction RNA splicing occurs in the nucleus when noncoding sequences (introns) are removed from the pre-mRNA transcript and coding sequences (exons) are joined to form a mature mRNA [1,2]. This reaction is catalyzed by a multiprotein complex called spliceosome. The spliceosome consists of five
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Hippo pathway proteins could synergistically regulate germ c
2022-08-24
Hippo pathway proteins could synergistically regulate germ cell development with some specific receptors. Kassab et al. [27] found that epidermal growth factor (EGF) receptor was localized in testicular germ Fluorescein-12-dUTP receptor and played important roles in bovine spermatogenesis. Likewise
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br Methods br Results br Discussion Exercise results
2022-08-24
Methods Results Discussion Exercise results in a remarkable redistribution of blood flow, which increases in active skeletal muscles but decreases in the splanchnic circulation. The regional blood flow in the kidney, spleen, stomach and intestine was measured by using the microsphere techn
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Most hexokinases are widely expressed but distinct
2022-08-24
Most hexokinases are widely expressed but distinct hexokinases predominate specific tissues (Katzen and Schimke, 1965, Rogers et al., 1975). Hexokinase I is found in all mammalian tissues, but is most abundant in the how to find molarity of solution and kidney (griffin et al., 1992). Hexokinase II
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