• The animal model described here is also expected to lead

  2019-05-05

  

  The animal model described here is also expected to lead us to design mechanism-based therapeutic interventions for bone metastases of NB. In this context, it is notable that the selective COX-2 inhibitor NS-398, which is known to selectively inhibit COX-2 without affecting COX-1 activity [30], inhi

• br Introduction Bone marrow adipocytes

  2019-05-05

  

  Introduction Bone marrow adipocytes are one of the most abundant cell types found in bone marrow tissue. They constitute approximately 15% of the bone marrow volume in young adults, rising to 60% by the age of 65 years old [1]. Previously considered as inert space filling cells with little biolog

• br Conflict of interest br Acknowledgments This study was su

  2019-05-05

  

  Conflict of interest Acknowledgments This study was supported by the National Natural Science Foundation of China (Nos. 81273501 and 81470378). Introduction Sudden cardiac death (SCD) is a tragic event and the aftermath is devastating to the surviving family and community. SCD occurs in ne

• The study by Wan Ling

  2019-05-05

  

  The study by Wan Ling Wong and colleagues examines the overall prevalence of age-related macular degeneration. In agreement with previous studies, Wong and colleagues have projected that 196 million people will be affected by age-related macular degeneration in 2020, increasing to 288 million by 204

• El sujeto de la enunciaci n se subordina a la

  2019-05-05

  

  El sujeto de la enunciación se subordina VE-822 la autoridad y dominio del príncipe y, por interpósita persona del rey, como súbdito y leal servidor: “[…] tuve por conveniente servir a vuestra alteza con este sumario brevísimo de muy difusa hystoria que de los estragos e perdiciones acaecidas se pod

• Recordemos que en diciembre de se celebr en

  2019-05-05

  

  Recordemos que en diciembre de 1938 se celebró en Lima la Octava Conferencia Internacional de los Estados Americanos, donde se analizó la Segunda Guerra Mundial y las posibles consecuencias para América, así como el rol de Estados Unidos, aunque no se aprobó ninguna acción colectiva. La Declaración

• br In its July editorial drew

  2019-05-05

  

  In its July editorial, drew attention to the ethical challenges posed by the Zika GW 610 manufacturer outbreak. The Regional Program on Bioethics at the Pan American Health Organization (PAHO) arranged an ethics consultation, funded by the Wellcome Trust, to provide ethically sound guidance for

• br Results There were cases where cryotherapy was used

  2019-05-04

  

  Results There were 232 cases where cryotherapy was used in 214 patients between 1994 and 2015. There were 96 male and 118 female. The age of patients ranged from 4 to 95. All patients had undergone imaging studies for evaluation. A majority of cases consisted of active or aggressive benign tumors

• br Discussion Debate persists about how to best define

  2019-05-04

  

  Discussion Debate persists about how to best define the ER ECG pattern. There is consensus regarding definition of the malignant form of ER as a J-point elevation that could be (or not) associated with ST elevation [1]. In this case, a clear J-point elevation was seen, particularly in lead III (F

• br Methods br Results br

  2019-05-04

  

  Methods Results Discussion Conclusions Conflict of interest statement Introduction The origin of a nonsustained ventricular tachycardia (NSVT) can usually be estimated with the 12-lead electrocardiogram (ECG) [1–3]; however, anatomical abnormalities sometimes make it difficult to c

• br What is the best pacing algorithm for vasovagal

  2019-05-04

  

  What is the best pacing algorithm for vasovagal syncope? Conclusions Conflict of interest Introduction The number of implantations of cardiovascular implantable electronic devices (CIEDs), including permanent pacemakers (PPMs), implantable cardioverter defibrillators (ICDs), and cardiac

• In advanced GIST patients where

  2019-05-04

  

  In advanced GIST patients where a course of treatment of Imatinib is interrupted by disease progression, subsequent rechallenge with Imatinib restored tumor control in most patients. In the prospective BFR14 trial, 25 patients with disease progression after interruption of one year of treatment rest

• Approximately of the patients who developed BM

  2019-05-04

  

  Approximately 50% of the patients who developed BM during their palliative disease course received BM-related radiotherapy and/or surgery; 12% of the patients received both therapy options. Our data confirms that the majority of patients with BM will respond to a low course of radiotherapy with good

• Despu s de marcharse de la India Paz publica una

  2019-05-04

  

  Después de marcharse de la India Paz publica , una obra ensayística que sirve como continuación de y comentario sobre la revuelta de los estudiantes mexicanos que precedió Aprotinin la masacre. En este libro Paz postula que la corrupción del lenguaje es la primera señal de un problema grave a nivel

• Por ltimo una divergencia crucial entre los bestiarios y las

  2019-05-04

  

  Por último, una divergencia crucial entre los bestiarios y las historias naturales está en la característica glosa alegórica que condujo la lectura moral de la order NHS Biotin en el Bestiario; en la historia natural primó una lectura literal o “histórica” que se finca en la experiencia de los senti

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