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FUS binds to DNA as well as to
2018-11-08
FUS binds to DNA as well as to RNA and regulates the expression of many transcripts in multiple steps of the gene regulation process (Dormann and Haass, 2013). In this study, we used FALS MPCs efficiently oriented into neuronal lineages including HB9-positive motor neurons to observe altered gene re
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br Acknowledgments The study is supported by funds
2018-11-08
Acknowledgments The study is supported by funds to W-Q.G. from the Chinese Ministry of Science and Technology (2012CB966800, 2013CB945600, and 2012CB967903), the National Natural Science Foundation of China (81130038 and 81372189), the Science and Technology Commission of Shanghai Municipality (P
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GLPG0634 Gaikwad and Gupta associate acid
2018-11-07
Gaikwad and Gupta (2008) associate GLPG0634 mine drainage, also known as abandoned mine drainage, to the reaction of water and oxygen specifically with coal mining. Water passing through the rocks from mining operations that have been deposited on the surface and the underground voids left behind b
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As to the degree of interest rate smoothing it is
2018-11-07
As to the degree of interest rate smoothing (), it is believed to follow a beta distribution with a mean of 0.6 and a standard deviation of 0.15, as pointed out by Castro (2011). The other Taylor rule parameters (, and ) are assumed to follow a gamma distribution with a mean of 0.5 and a standard d
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La Econof sica aplica el formalismo de la F
2018-11-07
La Econofísica[3] aplica el formalismo de la Física Estadística en la descripción de los sistemas financieros. Comúnmente cuando uno estudia los sistemas económicos es posible tener una apreciación de la esfera macro y micro. Sin embargo, es casi imposible tener un algoritmo o relación matemática qu
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Sea cual fuere la explicaci n de las
2018-11-07
Sea cual fuere la explicación de las causas del estancamiento económico, lo que es un hecho obvio es que ha llevado buy EHop-016 la caída del Producto Interno Bruto (pib). Según cifras oficiales en el periodo 1982-2010 el pib sólo creció en promedio anual un 2.2%, mientras que en 1933-1981 fue de 6.
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Activation of the proto oncogene c myc is associated
2018-11-07
Activation of the proto-oncogene c-myc is associated with cellular growth and proliferation programs (Dang, 2013) and is therefore an important feature of cancer initiation and maintenance (Gabay et al., 2014). Furthermore, c-myc induces the expression of telomerase reverse transcriptase (TERT) and
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br Materials and Methods br Results br Discussion The thorac
2018-11-07
Materials and Methods Results Discussion The thoracic aortic aneurysm in BAV patients frequently involves ascending aorta, where the SMCs are derived from the neural crest. In contrast, patients with BAV rarely have aneurysms involving the descending thoracic aorta, and the SMCs in this reg
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A number of clinical proteomics studies have
2018-11-07
A number of clinical proteomics studies have generated a long list of candidate urine protein biomarkers of various diseases (Beretov et al., 2015; Goodison et al., 2009; Rodriguez-Suarez et al., 2014; Shao, 2015); however, no biomarkers derived from ‘discovery’ studies were successfully translated
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Developing an Artificial Bacterial Consortium to Modulate
2018-11-07
Developing an Artificial Bacterial Consortium to Modulate Microbiota of Frail Elderly The microbial composition of the gut changes gradually with aging and is influenced by habitual diet and health status. In one cohort studied, frail elderly had a microbiota profile characterized by an increase in
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br Identification of candidate DRPs using
2018-11-07
Identification of candidate DRPs using mass spectrometry The candidate DRPs were excised from preparative CBB-stained gels and subjected to the nano-LC–MS/MS analysis. Out of 125 leaf and 112 root protein spots analyzed, 73 and 40 protein species were identified, respectively, representing 49 uni
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br Experimental design materials and methods br Conflicts of
2018-11-07
Experimental design, materials and methods Conflicts of interest Acknowledgments This study was founded by grants from CNPq (Conselho Nacional do Desenvolvimento Científico e Tecnológico - process 302885/2011-0) and CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior). Mirian
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br Acknowledgements br Data The concentration levels of urin
2018-11-07
Acknowledgements Data The concentration levels of urinary metal summarized in Tables 1 and 2. Table 1 shows the concentration of metal measured in two areas. Detection limits (LOD) of each metal is also shown in Table 1. Table 2 presents data in sex groups in polluted area. All metal levels a
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Another interesting finding of our study is that with the
2018-11-07
Another interesting finding of our study is that with the increasing N170 amplitude for characters, the amplitude of faces decreased at the same time especially in the left hemisphere after visual learning Chinese characters. Li et al.’s study finds that young children\'s reading ability has a negat
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Typical synaptic refinement processes during early adolescen
2018-11-07
Typical synaptic refinement processes during early adolescence are in the context of long-term depression and potentiation of cortical neurons in order to facilitate neuronal remodeling. Thus, the normal course of early adolescent development is uniquely vulnerable to disruption by MJ due to the ele
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