• The effects of zoledronic acid are most likely due to

  2019-06-15

  

  The effects of zoledronic glycogen synthase kinase are most likely due to impairment of the tumour-driven alterations to the bone microenvironment. This may render the bone marrow cavity unfavourable for metastatic growth, potentially redirecting tumour cells to other sites, including the periostea

• elastase inhibitor An incisional biopsy was undertaken Peri

  2019-06-15

  

  An incisional biopsy was undertaken. Peri-operative examination of the lesion revealed an expansile tumor mass brownish in color with focal whitish areas (Fig. 3). The lesion could be delineated from the surrounding cortical bone, and surrounding soft tissues. Histopathologically the biopsy material

• citco br Material and methods br

  2019-06-15

  

  Material and methods Results Discussion Previously, various small studies reported that CRT is an effective therapy in patients with NAHF [7,10–15]. These studies demonstrated favorable outcomes in patients treated with CRT, including the ability to wean patients from intravenous inotropes

• br Conflict of interest br Acknowledgments This study

  2019-06-15

  

  Conflict of interest Acknowledgments This study was supported by the National Natural Science Foundation of China (Nos. 81273501 and 81470378). Introduction Sudden cardiac death (SCD) is a tragic event and the aftermath is devastating to the surviving family and community. SCD occurs in ne

• The principal difference between BrS and ERS

  2019-06-15

  

  The principal difference between BrS and ERS is related to the region of the ventricle most affected. Epicardial mapping studies in BrS patients report accentuated J waves and fragmented and/or late potentials in the epicardial region of the RVOT [129–131], whereas in ERS only accentuated J waves, p

• The effectiveness of the intervention varied across district

  2019-06-15

  

  The effectiveness of the intervention varied across districts, with the proportion of infections averted inversely related to pre-intervention consistent condom use (appendix). Understandably, for districts in which previous interventions had already led to high consistent condom use among high-risk

• Paratyphi A could have a large effect if

  2019-06-15

  

  Paratyphi A could have a large effect if Vi-polysaccharide-conjugate vaccines are introduced in Asia. The absence of the Vi-polysaccharide caffeic acid in Paratyphi A is the most important microbiological discrepancy between Paratyphi A and Typhi; vaccines based on Vi-polysaccharide do not provide a

• La no intervenci n en los asuntos

  2019-06-15

  

  La no intervención en los asuntos de otro Estado no significa indiferencia ante los problemas que éste pueda tener. En efecto, algunos usos y gestiones pueden perjudicar glucose transporter países vecinos y también al mismo Estado que las realiza. Es por esto que la soberanía no resulta absoluta en

• En muchos estudios fuera del campo posfundacional

  2019-06-15

  

  En muchos estudios (fuera del campo posfundacional) la referencia AICAR Laclau proviene de teorizar el “discurso populista”. Existe un frecuente equívoco que es interpretar esto como una reducción a una especie de lenguaje populista. Al respecto, el esfuerzo de Laclau por establecer el estatus de su

• El eje dram tico de En

  2019-06-14

  

  El eje dramático de En la prisión… se va desarrollando domoic acid través de los relatos que el Profesor, un militante de la vanguardia política revolucionaria cubana, sueña que, a su vez sueña, que narra a un grupo de “negros” durante un agobiante verano habanero de los años noventa. Todo sucede de

• African leaders are gathering in Addis Ababa Ethiopia

  2019-06-14

  

  African leaders are gathering in Addis Ababa, Ethiopia, this week for the first ever . The event brings together government officials, including minsters of finance, technical experts, and policymakers, with the goal of advancing the coverage of life-saving immunisations across the continent. In

• In summary current evidence suggests that bone

  2019-06-14

  

  In summary, current evidence suggests that bone-targeted agents reduce morbidity from metastatic disease to bone, and potentially improve quality of life in patients with metastatic breast cancer. As there are costs and potential adverse effects associated with these agents, care should be taken in

• Treatment administered thereafter involved approaches Becaus

  2019-06-14

  

  Treatment administered thereafter involved 2 approaches. Because the patient had LV dyssynchrony with LBBB, we planned to implant a biventricular pacing device. A CRT-D was chosen despite the absence of syncope and non-sustained ventricular tachycardia. The choice of the device was based on the pres

• br Discussion Variant angina was described by Prinzmetal et

  2019-06-14

  

  Discussion Variant corticotropin releasing factor was described by Prinzmetal et al. in 1959 [1]. It can involve serious arrhythmias such as ventricular tachycardia, ventricular fibrillation, and atrioventricular block, and patients are particularly susceptible to sudden cardiac death in such cas

• br Discussion The cardiac manifestations

  2019-06-14

  

  Discussion The cardiac manifestations of organophosphorus poisoning are well known, involving various electrocardiographic abnormalities that may range from sinus tachycardia to ST elevation. Such most common abnormalities are sinus bradycardia, prolonged QT interval, and ST elevation [2–4]. Most

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