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br A new model of human wellbeing is
2019-06-18

A new model of human wellbeing is emerging to guide humanity in the Anthropocene. In essence, it recognises that wellbeing depends on enabling every person to lead a life of dignity and opportunity, while safeguarding the integrity of Earth\'s life-supporting systems. The conceptual framework of s
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Findings Final data analysis included households nine from t
2019-06-18

Findings Final data analysis included 28 households: nine from the Tulip filter group, 10 from Waterguard chlorination, and nine from the group who boiled water. Two households had incomplete data and were excluded from analysis. Before the intervention, 29 of 30 households were not treating their w
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Findings Overall households reported positive expenditure on
2019-06-18

Findings Overall, 8693 (71·02 %) households reported positive expenditure on tobacco (smoking, smokeless, or both), and were classified as any-tobacco users. Of these 8693 households, 2061 (16·8%) used smoking tobacco only, 3284 (26·8%) used smokeless tobacco only, and 3348 (27·4%) used both. After
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br For more than a decade WHO has focused its
2019-06-18

For more than a decade, WHO has focused its efforts against infectious diseases in Africa on HIV, tuberculosis, and malaria. HIV benefited from unprecedented efforts to enable diagnosis and prevention of transmission and to provide therapy at low cost. National networks of health clinics, transpor
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The time to use the distraction
2019-06-18

The time to use the distraction–osteogenesis apparatus in children was suggested to be after infection eradication. We used the Ilizarov apparatus immediately following radical debridement to provide stability and prepare for distraction–compression osteogenesis 1 week later. Circular external fixa
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br Materials and methods br
2019-06-18

Materials and methods Results Discussion In recent years, it has been revealed that miRNAs are critical members of complex regulatory systems. SNPs or mutations occurring in the miRNA gene region may disturb the properties of miRNAs and result in defect in protein translation of target mRNA
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The patient has fared well without any lead
2019-06-18

The patient has fared well, without any lead malfunctions, lead dislodgement, or inappropriate shocks. Follow-up echocardiography showed no aggravation of tricuspid regurgitation. Sufficiently high atrial and ventricular amplitudes (P-wave: 3.5mV and R-wave: 9.9mV) were confirmed during 18 months of
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Successful and safe catheter ablation is
2019-06-18

Successful and safe catheter ablation is facilitated by an appreciation for anatomical particularities and surgical details. Morphological analysis of clinically documented VT is also important. In these patients, VT usually shows a left bundle branch block-like QRS morphology and inferior frontal p
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Current ASCO recommendations suggest initiating bisphosphona
2019-06-18

Current ASCO recommendations suggest initiating bisphosphonate therapy in myeloma when there is evidence of bone involvement [124]. The optimal duration and frequency of bisphosphonate therapy for myeloma are not well understood and are currently being studied. All randomized, placebo-controlled tri
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Conflicting findings have been reported on the
2019-06-18

Conflicting findings have been reported on the survival and function recovery between treatments of LSS and amputation in patients with osteosarcoma. Toward this end, a meta-analysis of published clinical trials was performed to compare the clinical efficacy of LSS and amputation treatments in terms
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Performing an ajmaline test in children is problematic
2019-06-18

Performing an ajmaline test in children is problematic for 2 reasons. First, the test is apparently less sensitive in children than in adults. In fact, in 1 study, a repeat ajmaline challenge performed after puberty unmasked BrS in 23% of relatives with a previously negative drug test performed duri
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br Conflict of Interest br Acknowledgments
2019-06-18

Conflict of Interest Acknowledgments Introduction Human ether-a-go-go-related gene (hERG) encodes the alpha subunit of the rapidly-activating delayed-rectifier K+ channel, which plays a pivotal role in repolarization of cardiac action potentials (APs) [1]. Most of mutant hERG proteins causi
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The National Family Health Survey of India
2019-06-18

The National Family Health Survey of India emphasises the need to hydrate children who have diarrhoea, but there is no evidence to show that such an intervention in the home setting improves mortality. The eight out of ten practitioners who are unaware of childhood pneumonia symptoms in the developi
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Amiodarone has been used in Japan for
2019-06-17

Amiodarone has been used in Japan for more than 5 years now since its approval in July 2007, and intravenous amiodarone has been widely used for life-threatening ventricular tachycardia in the setting of critical care medicine. However, only few reports have been published in the international liter
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br Historical overview Before the development of screw
2019-06-17

Historical overview Before the development of screw-in leads, several types of non-screw pacing leads were designed to passively attach to the W-7 hydrochloride muscle with tips of different shapes, including straight, fringed, finned, or tined. However, a high incidence of dislodgement was a ma
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