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Several studies have shown a complex pattern of
2018-11-08
Several studies have shown a complex pattern of Ahr expression during early mouse embryogenesis. Fertilized eggs at the 1-cell stage show detectable levels of Ahr mRNA (Dey and Nebert, 1998; Wu et al., 2002) and high levels of AHR activity, as determined by an elevated constitutive mRNA level of the
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br Introduction Pancreatic ductal adenocarcinoma remains one
2018-11-08
Introduction Pancreatic ductal adenocarcinoma remains one of the most aggressive and devastating tumor malignancies with an overall 5-year survival rate of less than 5% (Kern et al., 2011). The only potentially curative treatment is the complete surgical resection of the tumor. Nevertheless, even
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br Materials and methods br Results br Discussion In
2018-11-08
Materials and methods Results Discussion In these experiments, we sought to determine the influence of gravitational mechanical unloading on the regenerative ability of bone marrow progenitors and specifically hypothesized that exposure to microgravity may alter the differentiation of bone
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Allogeneic non matched cloned male EGFP transduced porcine
2018-11-08
Allogeneic, non-matched, cloned male EGFP-transduced porcine eCSCs, were administered intracoronary in white Yorkshire female pigs, 30min after MI and coronary reperfusion (Ellison et al., 2009). Pig serum was injected to control pigs after MI (CTRL). The ganciclovir or sera were injected through a
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It is known that radiation also
2018-11-08
It is known that radiation also alters the SVZ microenvironment. Using a computed tomography-guided localized radiation technique, a study demonstrated that the intact SVZ NSCs failed to migrate across the irradiated RMS, suggesting that the microenvironment becomes hostile for cell invasion after r
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br Results br Discussion Human fetal dorsal skin from
2018-11-08
Results Discussion Human fetal dorsal skin, from which the fetal keratinocytes were cultured for this study, was analyzed histologically to correlate morphologic changes of the skin to biochemical changes in structural proteins during development. K18, which along with K8 is typical of simple
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In the controversial field of pluripotent stem cell research
2018-11-08
In the controversial field of pluripotent stem cell research, it is vital to argue on the basis of reliable and solid data that best reflect the actual research situation and are carefully validated. However, available data on recent research activities in this field are often based on abstract sear
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ALW-II-41-27 The laminins used in our
2018-11-08
The laminins used in our system were selected because of their importance in the developing ALW-II-41-27 (Domogatskaya et al., 2012; Miner et al., 2004), the regenerating liver (Martinez-Hernandez and Amenta, 1995; Carlsson et al., 1981), and the liver stem cell niche (Tanimizu et al., 2012; Lorenzi
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We believe that the production of homogeneous and functional
2018-11-08
We believe that the production of homogeneous and functional PSC-derived ventricular CMs using a non-transgenic approach will open new avenues for basic research and clinical applications. First, a pure population of ventricular CMs generated by the MB-based method offers a safer and more effective
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FUS binds to DNA as well as to
2018-11-08
FUS binds to DNA as well as to RNA and regulates the expression of many transcripts in multiple steps of the gene regulation process (Dormann and Haass, 2013). In this study, we used FALS MPCs efficiently oriented into neuronal lineages including HB9-positive motor neurons to observe altered gene re
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br Acknowledgments The study is supported by funds
2018-11-08
Acknowledgments The study is supported by funds to W-Q.G. from the Chinese Ministry of Science and Technology (2012CB966800, 2013CB945600, and 2012CB967903), the National Natural Science Foundation of China (81130038 and 81372189), the Science and Technology Commission of Shanghai Municipality (P
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GLPG0634 Gaikwad and Gupta associate acid
2018-11-07
Gaikwad and Gupta (2008) associate GLPG0634 mine drainage, also known as abandoned mine drainage, to the reaction of water and oxygen specifically with coal mining. Water passing through the rocks from mining operations that have been deposited on the surface and the underground voids left behind b
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As to the degree of interest rate smoothing it is
2018-11-07
As to the degree of interest rate smoothing (), it is believed to follow a beta distribution with a mean of 0.6 and a standard deviation of 0.15, as pointed out by Castro (2011). The other Taylor rule parameters (, and ) are assumed to follow a gamma distribution with a mean of 0.5 and a standard d
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La Econof sica aplica el formalismo de la F
2018-11-07
La Econofísica[3] aplica el formalismo de la Física Estadística en la descripción de los sistemas financieros. Comúnmente cuando uno estudia los sistemas económicos es posible tener una apreciación de la esfera macro y micro. Sin embargo, es casi imposible tener un algoritmo o relación matemática qu
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Sea cual fuere la explicaci n de las
2018-11-07
Sea cual fuere la explicación de las causas del estancamiento económico, lo que es un hecho obvio es que ha llevado buy EHop-016 la caída del Producto Interno Bruto (pib). Según cifras oficiales en el periodo 1982-2010 el pib sólo creció en promedio anual un 2.2%, mientras que en 1933-1981 fue de 6.
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