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Activation of the proto oncogene c myc is associated
2018-11-07
Activation of the proto-oncogene c-myc is associated with cellular growth and proliferation programs (Dang, 2013) and is therefore an important feature of cancer initiation and maintenance (Gabay et al., 2014). Furthermore, c-myc induces the expression of telomerase reverse transcriptase (TERT) and
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br Materials and Methods br Results br Discussion The thorac
2018-11-07
Materials and Methods Results Discussion The thoracic aortic aneurysm in BAV patients frequently involves ascending aorta, where the SMCs are derived from the neural crest. In contrast, patients with BAV rarely have aneurysms involving the descending thoracic aorta, and the SMCs in this reg
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A number of clinical proteomics studies have
2018-11-07
A number of clinical proteomics studies have generated a long list of candidate urine protein biomarkers of various diseases (Beretov et al., 2015; Goodison et al., 2009; Rodriguez-Suarez et al., 2014; Shao, 2015); however, no biomarkers derived from ‘discovery’ studies were successfully translated
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Developing an Artificial Bacterial Consortium to Modulate
2018-11-07
Developing an Artificial Bacterial Consortium to Modulate Microbiota of Frail Elderly The microbial composition of the gut changes gradually with aging and is influenced by habitual diet and health status. In one cohort studied, frail elderly had a microbiota profile characterized by an increase in
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br Identification of candidate DRPs using
2018-11-07
Identification of candidate DRPs using mass spectrometry The candidate DRPs were excised from preparative CBB-stained gels and subjected to the nano-LC–MS/MS analysis. Out of 125 leaf and 112 root protein spots analyzed, 73 and 40 protein species were identified, respectively, representing 49 uni
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br Experimental design materials and methods br Conflicts of
2018-11-07
Experimental design, materials and methods Conflicts of interest Acknowledgments This study was founded by grants from CNPq (Conselho Nacional do Desenvolvimento Científico e Tecnológico - process 302885/2011-0) and CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior). Mirian
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br Acknowledgements br Data The concentration levels of urin
2018-11-07
Acknowledgements Data The concentration levels of urinary metal summarized in Tables 1 and 2. Table 1 shows the concentration of metal measured in two areas. Detection limits (LOD) of each metal is also shown in Table 1. Table 2 presents data in sex groups in polluted area. All metal levels a
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Another interesting finding of our study is that with the
2018-11-07
Another interesting finding of our study is that with the increasing N170 amplitude for characters, the amplitude of faces decreased at the same time especially in the left hemisphere after visual learning Chinese characters. Li et al.’s study finds that young children\'s reading ability has a negat
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Typical synaptic refinement processes during early adolescen
2018-11-07
Typical synaptic refinement processes during early adolescence are in the context of long-term depression and potentiation of cortical neurons in order to facilitate neuronal remodeling. Thus, the normal course of early adolescent development is uniquely vulnerable to disruption by MJ due to the ele
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Regardless of whether such lists generated by
2018-11-07
Regardless of whether such lists generated by qualitative reviews (including both the Shulman and Nelson papers in this issue, but definitely not limited to them) are intended to be comprehensive or illustrative, we propose that it is well past time for us all to move beyond qualitative box-score ta
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Simulation theories propose that observation of another pers
2018-11-07
Simulation theories propose that observation of another person performing a facial expression activates the observer’s sensorimotor representations implicated in producing that movement, which aids expression recognition (e.g. Adolphs, 2006). Neurophysiological findings in monkeys have provided the
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Studies examining attention bias towards happy faces
2018-11-07
Studies examining attention bias towards happy faces are scarce. In the internalizing literature, increased attention towards happy faces is most commonly conceptualized as reflecting a bias towards rewards. Evidence suggesting that happy faces may be socially rewarding comes from fMRI studies in wh
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GSK2606414 Social psychologists have long recognized that
2018-11-07
Social psychologists have long recognized that the circumstances under which we are raised affect how we behave in, and think about, the world. For example, researchers have found that lower-SES children rely more on environmental explanations for events and outcomes, whereas higher-SES children ten
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caspase inhibitor In view of the benefits highlighted
2018-11-06
In view of the benefits highlighted in the preceding paragraph, BPE has continued to receive enormous research attention, especially in the developed countries as Meir et al. (2009) indicated. However, the existing studies on BPE focus more on office than residential buildings (see Gossauer, 2005; M
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Another dimension of livability that is customarily overlook
2018-11-06
Another dimension of livability that is customarily overlooked by either professional or global ranking surveys relates to the quality of life concerns of older adults. The American Association of Retired Persons (AARP) in the United States has emphasized the need to embed the concerns of the older
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